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• Heroin can lead to addiction, a form of substance use disorder. Withdrawal symptoms include muscle and bone pain, sleep problems, diarrhea and vomiting, and severe heroin cravings.
• Children under 16 who abuse prescription drugs are at greater risk of getting addicted later in life.
• Used illicitly, stimulants can lead to delirium and paranoia.
• Over 60 Million are said to have prescription for sedatives.
• Snorting amphetamines can damage the nasal passage and cause nose bleeds.
• Nearly one third of mushroom users reported heightened levels of anxiety.
• Almost 3 out of 4 prescription overdoses are caused by painkillers. In 2009, 1 in 3 prescription painkiller overdoses were caused by methadone.
• Snorting drugs can create loss of sense of smell, nosebleeds, frequent runny nose, and problems with swallowing.
• Research suggests that misuse of prescription opioid pain medicine is a risk factor for starting heroin use.
• A biochemical abnormality in the liver forms in 80 percent of Steroid users.
• Nearly 50% of all emergency room admissions from poisonings are attributed to drug abuse or misuse.
• Pharmacological treatment for depression began with MAOIs and tricyclics dating back to the 1950's.
• 2.5 million Americans abused prescription drugs for the first time, compared to 2.1 million who used marijuana for the first time.
• More than 29 percent of teens in treatment are dependent on tranquilizers, sedatives, amphetamines, and other stimulants (all types of prescription drugs).
• 52 Million Americans have abused prescription medications.
• Over 20 million individuals were abusing Darvocet before any limitations were put on the drug.
• Amphetamine withdrawal is characterized by severe depression and fatigue.
• Of the 500 metric tons of methamphetamine produced, only 4 tons is legally produced for legal medical use.
• These physical signs are more difficult to identify if the tweaker has been using a depressant such as alcohol; however, if the tweaker has been using a depressant, his or her negative feelings - including paranoia and frustration - can increase substantially.
• There were over 1.8 million Americans 12 or older who used a hallucinogen or inhalant for the first time. (1.1 million among hallucinogens)