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• Coca wine's (wine brewed with cocaine) most prominent brand, Vin Mariani, received endorsement for its beneficial effects from celebrities, scientists, physicians and even Pope Leo XIII.
• Pharmacological treatment for depression began with MAOIs and tricyclics dating back to the 1950's.
• During the 2000's many older drugs were reapproved for new use in depression treatment.
• Women abuse alcohol and drugs for different reasons than men do.
• Decreased access to dopamine often results in symptoms similar to Parkinson's disease
• Depressants are widely used to relieve stress, induce sleep and relieve anxiety.
• The duration of cocaine's effects depends on the route of administration.
• Heroin can lead to addiction, a form of substance use disorder. Withdrawal symptoms include muscle and bone pain, sleep problems, diarrhea and vomiting, and severe heroin cravings.
• LSD disrupts the normal functioning of the brain, making you see images, hear sounds and feel sensations that seem real but aren't.
• 12.4 million Americans aged 12 or older tried Ecstasy at least once in their lives, representing 5% of the US population in that age group.
• Crack Cocaine use became enormously popular in the mid-1980's, particularly in urban areas.
• Many people wrongly imprisoned under conspiracy laws are women who did nothing more than pick up a phone and take a message for their spouse, boyfriend, child or neighbor.
• Valium is a drug that is used to manage anxiety disorders.
• 19.3% of students ages 12-17 who receive average grades of 'D' or lower used marijuana in the past month and 6.9% of students with grades of 'C' or above used marijuana in the past month.
• The U.N. suspects that over 9 million people actively use ecstasy worldwide.
• Steroids can be life threatening, even leading to liver damage.
• Inhalants go through the lungs and into the bloodstream, and are quickly distributed to the brain and other organs in the body.
• Methadone was created by chemists in Germany in WWII.
• Slang Terms for Heroin:Smack, Dope, Junk, Mud, Skag, Brown Sugar, Brown, 'H', Big H, Horse, Charley, China White, Boy, Harry, Mr. Brownstone, Dr. Feelgood
• The Department of Justice listed the Chicago metro area as the top destination in the United States for heroin shipments.