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• Depressants, opioids and antidepressants are responsible for more overdose deaths (45%) than cocaine, heroin, methamphetamine and amphetamines (39%) combined
• Most heroin is injected, creating additional risks for the user, who faces the danger of AIDS or other infection on top of the pain of addiction.
• GHB is a popular drug at teen parties and "raves".
• Rates of K2 Spice use have risen by 80% within a single year.
• Marijuana is known as the "gateway" drug for a reason: those who use it often move on to other drugs that are even more potent and dangerous.
• About 50% of high school seniors do not think it's harmful to try crack or cocaine once or twice and 40% believe it's not harmful to use heroin once or twice.
• While the use of many street drugs is on a slight decline in the US, abuse of prescription drugs is growing.
• Alcohol-impaired driving fatalities accounted for 9,967 deaths (31 percent of overall driving fatalities).
• Ecstasy can stay in one's system for 1-5 days.
• Almost 50% of high school seniors have abused a drug of some kind.
• 2.5 million emergency department visits are attributed to drug misuse or overdose.
• One oxycodone pill can cost $80 on the street, compared to $3 to $5 for a bag of heroin. As addiction intensifies, many users end up turning to heroin.
• Nearly 170,000 people try heroin for the first time every year. That number is steadily increasing.
• Nearly 300,000 Americans received treatment for hallucinogens in 2011.
• Decreased access to dopamine often results in symptoms similar to Parkinson's disease
• 30,000 people may depend on over the counter drugs containing codeine, with middle-aged women most at risk, showing that "addiction to over-the-counter painkillers is becoming a serious problem.
• Methamphetamine (MA), a variant of amphetamine, was first synthesized in Japan in 1893 by Nagayoshi Nagai from the precursor chemical ephedrine.
• Excessive alcohol use costs the country approximately $235 billion annually.
• Women who drink have more health and social problems than men who drink
• 90% of Americans with a substance abuse problem started smoking marijuana, drinking or using other drugs before age 18.