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• Coca wine's (wine brewed with cocaine) most prominent brand, Vin Mariani, received endorsement for its beneficial effects from celebrities, scientists, physicians and even Pope Leo XIII.
• Popular among children and parents were the Cocaine toothache drops.
• In 2012, over 16 million adults were prescribed Adderall.
• 2.6 million people with addictions have a dependence on both alcohol and illicit drugs.
• Local pharmacies often bought - throat lozenges containing Cocaine in bulk and packaged them for sale under their own labels.
• Over 13.5 million people admit to using opiates worldwide.
• Smoking crack cocaine can lead to sudden death by means of a heart attack or stroke right then.
• A young German pharmacist called Friedrich Sertrner (1783-1841) had first applied chemical analysis to plant drugs, by purifying in 1805 the main active ingredient of opium
• Street gang members primarily turn cocaine into crack cocaine.
• Soon following its introduction, Cocaine became a common household drug.
• Of the 500 metric tons of methamphetamine produced, only 4 tons is legally produced for legal medical use.
• Smoking crack allows it to reach the brain more quickly and thus brings an intense and immediatebut very short-livedhigh that lasts about fifteen minutes.
• Unintentional deaths by poison were related to prescription drug overdoses in 84% of the poison cases.
• 10 million people aged 12 or older reported driving under the influence of illicit drugs.
• More than 9 in 10 people who used heroin also used at least one other drug.
• 12 to 17 year olds abuse prescription drugs more than they abuse ecstasy, crack/cocaine, heroin, and methamphetamine combined.
• In 1898 a German chemical company launched a new medicine called Heroin'
• The United States consumes over 75% of the world's prescription medications.
• Oxycontin has risen by over 80% within three years.
• Methamphetamine blocks dopamine re-uptake, methamphetamine also increases the release of dopamine, leading to much higher concentrations in the synapse, which can be toxic to nerve terminals.