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• Ecstasy is sometimes mixed with substances such as rat poison.
• Heroin was commercially developed by Bayer Pharmaceutical and was marketed by Bayer and other companies (c. 1900) for several medicinal uses including cough suppression.
• Many who overdose on barbiturates display symptoms of being drunk, such as slurred speech and uncoordinated movements.
• Fentanyl works by binding to the body's opioid receptors, which are found in areas of the brain that control pain and emotions.
• Over 60 Million are said to have prescription for sedatives.
• Phenobarbital was soon discovered and marketed as well as many other barbituric acid derivatives
• Studies in 2013 show that over 1.7 million Americans reported using tranquilizers like Ativan for non-medical reasons.
• In 2003, smoking (56%) was the most frequently used route of administration followed by injection, inhalation, oral, and other.
• According to the Department of Justice, the top destination in the United States for heroin shipments is the Chicago metro area.
• Over 13.5 million people admit to using opiates worldwide.
• Methamphetamine (MA), a variant of amphetamine, was first synthesized in Japan in 1893 by Nagayoshi Nagai from the precursor chemical ephedrine.
• During this time, Anti-Depressant use among all ages increased by almost 400 percent.
• The phrase 'dope fiend' was originally coined many years ago to describe the negative side effects of constant cocaine use.
• In 2014, there were over 39,000 unintentional drug overdose deaths in the United States
• 15.2% of 8th graders report they have used Marijuana.
• Cocaine use can lead to death from respiratory (breathing) failure, stroke, cerebral hemorrhage (bleeding in the brain) or heart attack.
• Morphine's use as a treatment for opium addiction was initially well received as morphine has about ten times more euphoric effects than the equivalent amount of opium. Over the years, however, morphine abuse increased.
• Krododil users rarely live more than one year after taking it.
• Rohypnol (The Date Rape Drug) is more commonly known as "roofies".
• There were over 190,000 hospitalizations in the U.S. in 2008 due to inhalant poisoning.