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• Pharmacological treatment for depression began with MAOIs and tricyclics dating back to the 1950's.
• Benzodiazepines are depressants that act as hypnotics in large doses, anxiolytics in moderate dosages and sedatives in low doses.
• In 2014, there were over 39,000 unintentional drug overdose deaths in the United States
• Because of the tweaker's unpredictability, there have been reports that they can react violently, which can lead to involvement in domestic disputes, spur-of-the-moment crimes, or motor vehicle accidents.
• Cocaine only has an effect on a person for about an hour, which will lead a person to have to use cocaine many times through out the day.
• In 2003, smoking (56%) was the most frequently used route of administration followed by injection, inhalation, oral, and other.
• 7.5 million have used cocaine at least once in their life, 3.5 million in the last year and 1.5 million in the past month.
• Gang affiliation and drugs go hand in hand.
• About 16 million individuals currently abuse prescription medications
• It is estimated that 80% of new hepatitis C infections occur among those who use drugs intravenously, such as heroin users.
• 6.5% of high school seniors smoke pot daily, up from 5.1% five years ago. Meanwhile, less than 20% of 12th graders think occasional use is harmful, while less than 40% see regular use as harmful (lowest numbers since 1983).
• An estimated 88,0009 people (approximately 62,000 men and 26,000 women9) die from alcohol-related causes annually, making alcohol the fourth leading preventable cause of death in the United States.
• Women born after World War 2 were more inclined to become alcoholics than those born before 1943.
• Ritalin can cause aggression, psychosis and an irregular heartbeat that can lead to death.
• Drug addicts are not the only ones affected by drug addiction.
• 90% of Americans with a substance abuse problem started smoking marijuana, drinking or using other drugs before age 18.
• In medical use, there is controversy about whether the health benefits of prescription amphetamines outweigh its risks.
• Almost 38 million people have admitted to have used cocaine in their lifetime.
• Depressants are highly addictive drugs, and when chronic users or abusers stop taking them, they can experience severe withdrawal symptoms, including anxiety, insomnia and muscle tremors.
• Substance abuse and addiction also affects other areas, such as broken families, destroyed careers, death due to negligence or accident, domestic violence, physical abuse, and child abuse.