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• Heroin addiction was blamed for a number of the 260 murders that occurred in 1922 in New York (which compared with seventeen in London). These concerns led the US Congress to ban all domestic manufacture of heroin in 1924.
• Nicotine is so addictive that many smokers who want to stop just can't give up cigarettes.
• Two of the most common long-term effects of heroin addiction are liver failure and heart disease.
• A heroin overdose causes slow and shallow breathing, blue lips and fingernails, clammy skin, convulsions, coma, and can be fatal.
• Foreign producers now supply much of the U.S. Methamphetamine market, and attempts to bring that production under control have been problematic.
• A 2007 survey in the US found that 3.3% of 12- to 17-year-olds and 6% of 17- to 25-year-olds had abused prescription drugs in the past month.
• The United States consumes 80% of the world's pain medication while only having 6% of the world's population.
• Amphetamine was first made in 1887 in Germany and methamphetamine, more potent and easy to make, was developed in Japan in 1919.
• Over 200,000 people have abused Ketamine within the past year.
• LSD (AKA: Acid, blotter, cubes, microdot, yellow sunshine, blue heaven, Cid): an odorless, colorless chemical that comes from ergot, a fungus that grows on grains.
• 90% of deaths from poisoning are directly caused by drug overdoses.
• Its rock form is far more addictive and potent than its powder form.
• Use of amphetamines is increasing among college students. One study across a hundred colleges showed nearly 7% of college students use amphetamines illegally. Over 25% of students reported use in the past year.
• Outlaw motorcycle gangs are primarily into distributing marijuana and methamphetamine.
• Methamphetamine blocks dopamine re-uptake, methamphetamine also increases the release of dopamine, leading to much higher concentrations in the synapse, which can be toxic to nerve terminals.
• Coca wine's (wine brewed with cocaine) most prominent brand, Vin Mariani, received endorsement for its beneficial effects from celebrities, scientists, physicians and even Pope Leo XIII.
• Of the 500 metric tons of methamphetamine produced, only 4 tons is legally produced for legal medical use.
• Oxycodone has the greatest potential for abuse and the greatest dangers.
• People who regularly use heroin often develop a tolerance, which means that they need higher and/or more frequent doses of the drug to get the desired effects.
• Approximately 1,800 people 12 and older tried cocaine for the first time in 2011.