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• Cocaine increases levels of the natural chemical messenger dopamine in brain circuits controlling pleasure and movement.
• Marijuana had the highest rates of dependence out of all illicit substances in 2011.
• Women born after World War 2 were more inclined to become alcoholics than those born before 1943.
• In medical use, there is controversy about whether the health benefits of prescription amphetamines outweigh its risks.
• Over 600,000 people has been reported to have used ecstasy within the last month.
• Over 750,000 people have used LSD within the past year.
• Over 20 million Americans over the age of 12 have an addiction (excluding tobacco).
• 193,717 people were admitted to Drug rehabilitation or Alcohol rehabilitation programs in California in 2006.
• Some designer drugs have risen by 80% within a single year.
• Powder cocaine is a hydrochloride salt derived from processed extracts of the leaves of the coca plant. 'Crack' is a type of processed cocaine that is formed into a rock-like crystal.
• Barbituric acid was first created in 1864 by a German scientist named Adolf von Baeyer. It was a combination of urea from animals and malonic acid from apples.
• Mixing Ativan with depressants, such as alcohol, can lead to seizures, coma and death.
• Emergency room admissions from prescription opiate abuse have risen by over 180% over the last five years.
• In the past 15 years, abuse of prescription drugs, including powerful opioid painkillers such as oxycodone and hydrocodone, has risen alarmingly among all ages, growing fastest among college-age adults, who lead all age groups in the misuse of medications.
• National Survey on Drug Use and Health found that more than 9.5% of youths aged 12 to 17 in the US were current illegal drug users.
• Most people try heroin for the first time in their late teens or early 20s. Anyone can become addictedall races, genders, and ethnicities.
• Nitrous oxide is a medical gas that is referred to as "laughing gas" among users.
• Coca wine's (wine brewed with cocaine) most prominent brand, Vin Mariani, received endorsement for its beneficial effects from celebrities, scientists, physicians and even Pope Leo XIII.
• Heroin use has increased across the US among men and women, most age groups, and all income levels.
• Ecstasy causes hypothermia, which leads to muscle breakdown and could cause kidney failure.