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• Methamphetamine blocks dopamine re-uptake, methamphetamine also increases the release of dopamine, leading to much higher concentrations in the synapse, which can be toxic to nerve terminals.
• Coca wine's (wine brewed with cocaine) most prominent brand, Vin Mariani, received endorsement for its beneficial effects from celebrities, scientists, physicians and even Pope Leo XIII.
• Pharmacological treatment for depression began with MAOIs and tricyclics dating back to the 1950's.
• 193,717 people were admitted to Drug rehabilitation or Alcohol rehabilitation programs in California in 2006.
• Some common street names for Amphetamines include: speed, uppers, black mollies, blue mollies, Benz and wake ups.
• 90% of people are exposed to illegal substance before the age of 18.
• Other psychological symptoms include manic behavior, psychosis (losing touch with reality) and aggression, commonly known as 'Roid Rage'.
• Amphetamines + some antidepressants: elevated blood pressure, which can lead to irregular heartbeat, heart failure and stroke.
• War veterans often turn to drugs and alcohol to forget what they went through during combat.
• Illegal drug use is declining while prescription drug abuse is rising thanks to online pharmacies and illegal selling.
• A tolerance to cocaine develops quicklythe addict soon fails to achieve the same high experienced earlier from the same amount of cocaine.
• Alcohol is a drug because of its intoxicating effect but it is widely accepted socially.
• Alcohol poisoning deaths are most common among ages 35-64 years old.
• The U.S. utilizes over 65% of the world's supply of Dilaudid.
• Depressants are widely used to relieve stress, induce sleep and relieve anxiety.
• Rates of valium abuse have tripled within the course of ten years.
• Emergency room admissions from prescription opiate abuse have risen by over 180% over the last five years.
• While the use of many street drugs is on a slight decline in the US, abuse of prescription drugs is growing.
• In 2014, Mexican heroin accounted for 79 percent of the total weight of heroin analyzed under the HSP.
• Most people use drugs for the first time when they are teenagers.