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• Cocaine increases levels of the natural chemical messenger dopamine in brain circuits controlling pleasure and movement.
• A person can become more tolerant to heroin so, after a short time, more and more heroin is needed to produce the same level of intensity.
• The largest amount of illicit drug-related emergency room visits in 2011 were cocaine related (over 500,000 visits).
• An estimated 208 million people internationally consume illegal drugs.
• Hallucinogens also cause physical changes such as increased heart rate, elevating blood pressure and dilating pupils.
• Medical consequences of chronic heroin injection abuse include scarred and/or collapsed veins, bacterial infections of the blood vessels and heart valves, abscesses (boils) and other soft-tissue infections, and liver or kidney disease.
• Over 10 million people have used methamphetamine at least once in their lifetime.
• Over 2.3 million adolescents were reported to be abusing prescription stimulant such as Ritalin.
• There were over 1.8 million Americans 12 or older who used a hallucinogen or inhalant for the first time. (1.1 million among hallucinogens)
• Non-pharmaceutical fentanyl is sold in the following forms: as a powder; spiked on blotter paper; mixed with or substituted for heroin; or as tablets that mimic other, less potent opioids.
• Heroin use has increased across the US among men and women, most age groups, and all income levels.
• The overall costs of alcohol abuse amount to $224 billion annually, with the costs to the health care system accounting for approximately $25 billion.
• The United States was the country in which heroin addiction first became a serious problem.
• Ecstasy increases levels of several chemicals in the brain, including serotonin, dopamine, and norepinephrine. It alters your mood and makes you feel closer and more connected to others.
• 60% of High Schoolers, 32% of Middle Schoolers have seen drugs used, kept or sold on school grounds.
• Studies in 2013 show that over 1.7 million Americans reported using tranquilizers like Ativan for non-medical reasons.
• According to the latest drug information from the National Institute on Drug Abuse (NIDA), drug abuse costs the United States over $600 billion annually in health care treatments, lost productivity, and crime.
• Colombia's drug trade is worth US$10 billion. That's one-quarter as much as the country's legal exports.
• Most heroin is injected, creating additional risks for the user, who faces the danger of AIDS or other infection on top of the pain of addiction.
• In the 20th Century Barbiturates were Prescribed as sedatives, anesthetics, anxiolytics, and anti-convulsants