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• Ecstasy causes chemical changes in the brain which affect sleep patterns, appetite and cause mood swings.
• In Russia, Krokodil is estimated to kill 30,000 people each year.
• The strongest risk for heroin addiction is addiction to opioid painkillers.
• Amphetamine withdrawal is characterized by severe depression and fatigue.
• Heroin creates both a physical and psychological dependence.
• In 1981, Alprazolam released to the United States drug market.
• Crack cocaine, a crystallized form of cocaine, was developed during the cocaine boom of the 1970s and its use spread in the mid-1980s.
• Methamphetamine is a synthetic (man-made) chemical, unlike cocaine, for instance, which comes from a plant.
• Around 16 million people at this time are abusing prescription medications.
• 30% of emergency room admissions from prescription abuse involve opiate-based substances.
• Almost 3 out of 4 prescription overdoses are caused by painkillers. In 2009, 1 in 3 prescription painkiller overdoses were caused by methadone.
• Over 13 million Americans have admitted to abusing CNS stimulants.
• High dosages of ketamine can lead to the feeling of an out of body experience or even death.
• 45% of people who use heroin were also addicted to prescription opioid painkillers.
• The United States consumes over 75% of the world's prescription medications.
• Psychic side effects of hallucinogens include the disassociation of time and space.
• Ambien can cause severe allergic reactions such as hives, breathing problems and swelling of the mouth, tongue and throat.
• In 2012, Ambien was prescribed 43.8 million times in the United States.
• Ecstasy is one of the most popular drugs among youth today.
• These physical signs are more difficult to identify if the tweaker has been using a depressant such as alcohol; however, if the tweaker has been using a depressant, his or her negative feelings - including paranoia and frustration - can increase substantially.