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• Production and trafficking soared again in the 1990's in relation to organized crime in the Southwestern United States and Mexico.
• A 2007 survey in the US found that 3.3% of 12- to 17-year-olds and 6% of 17- to 25-year-olds had abused prescription drugs in the past month.
• Alcohol is a drug because of its intoxicating effect but it is widely accepted socially.
• The United States spends over 560 Billion Dollars for pain relief.
• Drug abuse is linked to at least half of the crimes committed in the U.S.
• Short term rehab effectively helps more women than men, even though they may have suffered more traumatic situations than men did.
• Ecstasy is sometimes mixed with substances such as rat poison.
• Over 5 million emergency room visits in 2011 were drug related.
• The number of people receiving treatment for addiction to painkillers and sedatives has doubled since 2002.
• Ecstasy causes hypothermia, which leads to muscle breakdown and could cause kidney failure.
• Substance abuse costs the health care system about $11 billion, with overall costs reaching $193 billion.
• In Arizona during the year 2006 a total of 23,656 people were admitted to addiction treatment programs.
• Over 60 Million are said to have prescription for tranquilizers.
• 70% to 80% of the world's cocaine comes from Columbia.
• In medical use, there is controversy about whether the health benefits of prescription amphetamines outweigh its risks.
• 90% of Americans with a substance abuse problem started smoking marijuana, drinking or using other drugs before age 18.
• Nearly 23 Million people are in need of treatment for chemical dependency.
• In Connecticut overdoses have claimed at least eight lives of high school and college-age students in communities large and small in 2008.
• Inhalants are sniffed or breathed in where they are absorbed quickly by the lungs, this is commonly referred to as "huffing" or "bagging".
• Long-term use of painkillers can lead to dependence, even for people who are prescribed them to relieve a medical condition but eventually fall into the trap of abuse and addiction.