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• Drug abuse and addiction changes your brain chemistry. The longer you use your drug of choice, the more damage is done and the harder it is to go back to 'normal' during drug rehab.
• When injected, it can cause decay of muscle tissues and closure of blood vessels.
• During the 1850s, opium addiction was a major problem in the United States.
• By 8th grade, before even entering high school, approximately have of adolescents have consumed alcohol, 41% have smoked cigarettes and 20% have used marijuana.
• GHB is usually ingested in liquid form and is most similar to a high dosage of alcohol in its effect.
• Women who use needles run the risk of acquiring HIV or AIDS, thus passing it on to their unborn child.
• Snorting drugs can create loss of sense of smell, nosebleeds, frequent runny nose, and problems with swallowing.
• People inject, snort, or smoke heroin. Some people mix heroin with crack cocaine, called a speedball.
• Stimulants such as caffeine can be found in coffee, tea and most soft drinks.
• Of the 500 metric tons of methamphetamine produced, only 4 tons is legally produced for legal medical use.
• Almost 3 out of 4 prescription overdoses are caused by painkillers. In 2009, 1 in 3 prescription painkiller overdoses were caused by methadone.
• Barbiturates have been used for depression and even by vets for animal anesthesia yet people take them in order to relax and for insomnia.
• Women who abuse drugs are more prone to sexually transmitted diseases and mental health problems such as depression.
• 1 in every 9 high school seniors has tried synthetic marijuana (also known as 'Spice' or 'K2').
• The United States represents 5% of the world's population and 75% of prescription drugs taken. 60% of teens who abuse prescription drugs get them free from friends and relatives.
• In the course of the 20th century, more than 2500 barbiturates were synthesized, 50 of which were eventually employed clinically.
• Decreased access to dopamine often results in symptoms similar to Parkinson's disease
• Methamphetamine can cause cardiac damage, elevates heart rate and blood pressure, and can cause a variety of cardiovascular problems, including rapid heart rate, irregular heartbeat, and increased blood pressure.
• Some designer drugs have risen by 80% within a single year.
• Substance abuse and addiction also affects other areas, such as broken families, destroyed careers, death due to negligence or accident, domestic violence, physical abuse, and child abuse.