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• Methamphetamine blocks dopamine re-uptake, methamphetamine also increases the release of dopamine, leading to much higher concentrations in the synapse, which can be toxic to nerve terminals.
• Heroin is highly addictive and withdrawal extremely painful.
• Disability-Adjusted Life-Years (DALYs): A measure of years of life lost or lived in less than full health.
• An estimated 88,0009 people (approximately 62,000 men and 26,000 women9) die from alcohol-related causes annually, making alcohol the fourth leading preventable cause of death in the United States.
• Methamphetamine increases the amount of the neurotransmitter dopamine, leading to high levels of that chemical in the brain.
• The drug was outlawed as a part of the U.S. Drug Abuse and Regulation Control Act of 1970.
• The high potency of fentanyl greatly increases risk of overdose.
• About 72% of all cases reported to poison centers for substance use were calls from people's homes.
• 12 to 17 year olds abuse prescription drugs more than they abuse ecstasy, crack/cocaine, heroin, and methamphetamine combined.
• Illicit drug use in America has been increasing. In 2012, an estimated 23.9 million Americans aged 12 or olderor 9.2 percent of the populationhad used an illicit drug or abused a psychotherapeutic medication (such as a pain reliever, stimulant, or tranquilizer) in the past month. This is up from 8.3 percent in 2002. The increase mostly reflects a recent rise in the use of marijuana, the most commonly used illicit drug.
• Women who abuse drugs are more prone to sexually transmitted diseases and mental health problems such as depression.
• 6.5% of high school seniors smoke pot daily, up from 5.1% five years ago. Meanwhile, less than 20% of 12th graders think occasional use is harmful, while less than 40% see regular use as harmful (lowest numbers since 1983).
• Popular among children and parents were the Cocaine toothache drops.
• Ecstasy can cause kidney, liver and brain damage, including long-lasting lesions (injuries) on brain tissue.
• A heroin overdose causes slow and shallow breathing, blue lips and fingernails, clammy skin, convulsions, coma, and can be fatal.
• Interventions can facilitate the development of healthy interpersonal relationships and improve the participant's ability to interact with family, peers, and others in the community.
• Alcohol kills more young people than all other drugs combined.
• Colombia's drug trade is worth US$10 billion. That's one-quarter as much as the country's legal exports.
• The United States spends over 560 Billion Dollars for pain relief.
• In 2011, non-medical use of Alprazolam resulted in 123,744 emergency room visits.