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• 300 tons of barbiturates are produced legally in the U.S. every year.
• Invisible drugs include coffee, tea, soft drinks, tobacco, beer and wine.
• While the use of many street drugs is on a slight decline in the US, abuse of prescription drugs is growing.
• Other psychological symptoms include manic behavior, psychosis (losing touch with reality) and aggression, commonly known as 'Roid Rage'.
• Over 2.3 million people admitted to have abused Ketamine in their lifetime.
• Most people use drugs for the first time when they are teenagers. There were just over 2.8 million new users (initiates) of illicit drugs in 2012, or about 7,898 new users per day. Half (52 per-cent) were under 18.
• Depressants are widely used to relieve stress, induce sleep and relieve anxiety.
• The number of habitual cocaine users has declined by 75% since 1986, but it's still a popular drug for many people.
• Each year, over 5,000 people under the age of 21 die from Alcohol-related incidents in the U.S alone.
• In medical use, there is controversy about whether the health benefits of prescription amphetamines outweigh its risks.
• Adderall is linked to cases of sudden death due to heart complications.
• Ritalin can cause aggression, psychosis and an irregular heartbeat that can lead to death.
• In 1981, Alprazolam released to the United States drug market.
• The duration of cocaine's effects depends on the route of administration.
• More than half of new illicit drug users begin with marijuana. Next most common are prescription pain relievers, followed by inhalants (which is most common among younger teens).
• Heroin was first manufactured in 1898 by the Bayer pharmaceutical company of Germany and marketed as a treatment for tuberculosis as well as a remedy for morphine addiction.
• When injected, it can cause decay of muscle tissues and closure of blood vessels.
• Increased or prolonged use of methamphetamine can cause sleeplessness, loss of appetite, increased blood pressure, paranoia, psychosis, aggression, disordered thinking, extreme mood swings and sometimes hallucinations.
• During the 2000's many older drugs were reapproved for new use in depression treatment.
• Nitrous oxide is a medical gas that is referred to as "laughing gas" among users.